How Disregulation in Genes Contribute to the Development of Cancer
Dr. Sara Zaccara's research examines the RNA life cycle, with a focus on RNA modifications and their roles in gene expression regulation. Her lab explores how dysregulation of RNA processes contributes to diseases, particularly Acute Myeloid Leukemia and Myelodysplastic Syndromes. By investigating these complex RNA profiles, Dr. Zaccara aims to uncover novel therapeutic targets. Her interdisciplinary approach combines biochemistry, molecular biology, and computational methods, enabling a comprehensive exploration of RNA regulatory mechanisms. Dr. Zaccara's work has advanced our understanding of RNA's dynamic functions and its impact on cellular homeostasis. Her contributions have already highlighted RNA targets for innovative treatments now in clinical trials.
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